People that have been diagnosed with Parkinson’s disease may be at risk for developing another type of this condition. The symptoms of PD include tremors, rigidity and loss of balance. In addition to the outward signs there are other issues with the brain tissue that can be an underlying issue for some people. In this article we will look at two potential causes of PD.
Carbidopa-levodopa is one potential cause of PD. This chemical has been found to be elevated in certain Parkinson’s patients. While it is not clear what the cause of this is, it is being studied as a treatment for this condition. The levels of carbidopa-levodopa may be elevated because of a lack of properly working enzymes in the body. This has been shown in animal studies to occur in certain diseases. Some research has suggested that using carbidopa-levodopa may slow down the progression of Parkinson’s disease.
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Another possible cause of PD is protein lipase deficiency. This results in the body not producing enough cholesterol which then leads to the symptoms of parkinsonism. When there is an insufficient amount of cholesterol in the body it can lead to cholesterol build up in the brain which ultimately results in symptoms such as tremor. Studies have not shown any correlation between cholesterol and PD so further studies are needed to support this claim. There are medications on the market that can help you lower your cholesterol level so you would not necessarily need to take a medication to correct this symptom.
Loss of balance and rigidity can also be tied to this Parkinson’s disease symptom. With rigidity you will notice that you have trouble keeping your balance. You will start to have problems standing up or walking correctly. The loss of balance can make a person appear to be unsteady on their feet which can lead to tremors. Usually once these tremors have been established you will see them worsen which can make them difficult to diagnose.
Carbidopa-levodopa has been found to relieve symptoms of PD. It acts on brain tissue by increasing levels of dopamine. Dopamine is essential for muscle contraction, sensory impulses, emotional arousal, locomotion, speech and balance. A deficit in dopamine is believed to play a big role in many of the symptoms of PD. A study looking at how dopamine levels affect nerve cell membranes in mice showed that a compound in Carbidopa-levodopa can increase dopamine levels in the nerve cells which in turn stimulated nerve conduction.
Other symptoms of PD include rigidity, severe foot tremors and loss of balance. These symptoms may develop gradually or may show a direct relationship to PD. Researchers have found that certain chemicals in the body, particularly those in the dopamine system, can cause these symptoms to develop. There are currently no known cures for PD, but there are medications available to help control some of its symptoms. Carbidopa-levodopa and related compounds may be able to provide an additional therapy to those who suffer from parkinson’s disease.
